Formation of Rutin–β-Cyclodextrin Inclusion Complexes by Supercritical Antisolvent Precipitation
نویسندگان
چکیده
منابع مشابه
Supercritical antisolvent precipitation of PHBV microparticles.
The micronization of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) from organic solutions using supercritical antisolvent (SAS) technique has been successfully achieved. SAS experiments were carried out at different operational conditions and microspheres with mean diameters ranging from 3 to 9 microm were obtained. The effect of CO(2) and liquid flow, temperature and pressure on particle...
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One of the most important environmental concerns for the polymer industry is to produce new products with near-zero residual monomer content. A new process based on supercritical CO2 has been successfully tested for the extraction of the residual monomer and the simultaneous micronization of the polymer. The process has been tested on a pilot-scale plant. The reduction of methyl methacrylate (M...
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This thesis discusses particle production by supercritical antisolvent processing (SAS) techniques by looking the fundamentals and applications of the method with some case studies. The final aim of this work is however to consider the SAS particle production process feasibility. In the process studied the solid is dissolved in a conventional solvent and the solution is sprayed continuously thr...
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The supercritical antisolvent (SAS) technique was used to prepare ethyl cellulose/methyl cellulose blends, two biocompatible polymers commonly used as drug carriers in controlled delivery systems. Ethyl cellulose is widely used as a drug carrier. The drug release of the delivery devices can be controlled to some extent by addition of a water-soluble or water swellable polymer, such as methyl ce...
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One of the methods to enhance bio-accessibility of drugs like Acridone and its oxime is toform inclusion complexes with β-cyclodextrin. The formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. The aqueous phasesolubility studies reveal 1:1 stoichiometry between the compound and, β-cyclodextrin. The studyof thermodynamic parameters like ΔG,...
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ژورنال
عنوان ژورنال: Polymers
سال: 2021
ISSN: 2073-4360
DOI: 10.3390/polym13020246